中华眼底病杂志

中华眼底病杂志

厚脉络膜相关疾病

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厚脉络膜相关疾病(pachychoroid spectrum diseases)是指以局灶性或弥散性脉络膜增厚、脉络膜血管扩张及通透性增加、存在局部视网膜色素上皮(RPE)层浅脱离为特征的一系列疾病,包括厚脉络膜性RPE病变、厚脉络膜性新生血管病变、息肉样脉络膜血管病变和中心性浆液性脉络膜视网膜病变。现有证据提示厚脉络膜相关疾病之间存在密切联系。这些相似的特征和联系都提示它们可能具有同源性。深入了解厚脉络膜相关疾病的组成、典型形态改变,探讨其可能的发病机制具有重要的临床意义。

Pachychoroid spectrum diseases includes central serous chorioretinopathy (CSC), pachychoroid pigment epitheliopathy, pachychoroid neovasculopathy, and polypoidal choroidal vasculopathy, which share common characteristics, including focal or diffused increased choroidal thickness, choroidal hyper-permeability, and dilated choroidal vessels. These diseases are likely to represent a continuum of the same pathogenic process. Similar features and association among them suggest that they may have similar etiology. It is of great clinical significance to understand the composition and typical morphological changes of pachychoroid-related diseases and to explore its possible pathogenesis.

关键词: 中心性浆液性脉络膜视网膜病变/诊断; 脉络膜新生血管化/诊断; 视网膜色素上皮/病理学; 综述;  

Key words: Central serous chorioretinopathy/diagnosis; Choroidal neovascularization/diagnosis; Retinal pigment epithelium/pathology; Optical coherence tomography; Review

引用本文: 申晶晶, 袁源智. 厚脉络膜相关疾病. 中华眼底病杂志, 2017, 33(4): 424-427. doi: 10.3760/cma.j.issn.1005-1015.2017.04.027 复制

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